Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
Work
Year: 2020
Type: review
Abstract: The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutathione biosynthesis and antioxidant defense and is overexpressed in multiple human cancers. ... more
Source: Protein & Cell
Authors Pranavi Koppula, Li Zhuang, Boyi Gan
Institutions The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center at Houston
Cites: 132
Cited by: 1,473
Related to: 10
FWCI: 31.11
Citation percentile (by year/subfield): 99.97
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Sustainable Development Goal Good health and well-being
Open Access status: diamond